Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10797955 | 0.95 | GAA (0.56) | ALDH1A1PKMHTTPOLBKDM4E | |
| SCHEMBL10794650 | 0.91 | PKM (0.52) | ALDH1A1PKMHTTPOLBKDM4E | |
| SCHEMBL10799158 | 0.90 | GAA (0.56) | ALDH1A1PKMHTTPOLBKDM4E | |
| SCHEMBL10798877 | 0.88 | ALDH1A1 (0.57) | ALDH1A1PKMHTTPOLBKDM4E | |
| SCHEMBL10797861 | 0.88 | PKM (0.52) | ALDH1A1PKMHTTPOLBKDM4E | |
| SCHEMBL10800331 | 0.86 | ALDH1A1 (0.55) | ALDH1A1PKMHTTPOLBKDM4E | |
| SCHEMBL10799303 | 0.82 | LMNA (0.59) | ALDH1A1PKMHTTPOLBKDM4E | |
| SCHEMBL10795380 | 0.82 | PKM (0.56) | ALDH1A1PKMHTTPOLBKDM4E | |
| SCHEMBL10795181 | 0.81 | ALDH1A1 (0.50) | ALDH1A1PKMHTTPOLBKDM4E | |
| SCHEMBL10794407 | 0.81 | LMNA (0.48) | ALDH1A1PKMHTTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642348-A | ANTIARRHYTHMIA AGENTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-02-10 | — | — | US | disclosed |
| US-4593102-A | N-[(amino)alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulfur linked substitution in the 2, 3 or 4-position | A. H. ROBINS COMPANY, INC. (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0160436-A2 | N-[(Amino)Alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulphur linked substitution in the 2, 3 or 4-position | A.H. ROBINS COMPANY, INCORPORATED (US) | 1985-11-06 | — | — | EP | disclosed |