Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800136 | 0.80 | CHRM1 (0.63) | PTGS1CHRM1ALDH1A1MAPTCYP2C19 | |
| SCHEMBL10797372 | 0.78 | PTGS1 (0.40) | PTGS1CHRM1CNR1CNR2NPC1 | |
| SCHEMBL10797433 | 0.77 | PTGS1 (0.68) | PTGS1CHRM1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL8897255 | 0.76 | ALDH1A1 (0.45) | PTGS1ALDH1A1HTTLMNAPSEN1 | |
| SCHEMBL9865412 | 0.71 | MDM2 (0.40) | NPC1HTTRAB9ACYP3A4KDM4E | |
| SCHEMBL9420884 | 0.70 | CSNK2A1 (0.42) | PTGS1MAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8740464 | 0.69 | AKR1C3 (0.40) | ALDH1A1HTTKDM4ELMNATSPO | |
| SCHEMBL7012583 | 0.69 | METAP2 (0.44) | CNR1CNR2NPC1ALDH1A1RAB9A | |
| SCHEMBL4716198 | 0.68 | TP53 (0.44) | CNR1CNR2MAPTHTTL3MBTL1 | |
| SCHEMBL10797770 | 0.67 | PTGS1 (0.45) | PTGS1CHRM1CNR1CNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711879-A | IMMUNO-MODULATING ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1987-12-08 | — | — | US | claimed |
| US-4640911-A | IMMUNOSTIMULANTS, VIRICIDES SUCH AS HERPES SIMPLEX | CIBA-GEIGY CORPORATION (US) | 1987-02-03 | — | — | US | claimed |
| US-4711879-A | IMMUNO-MODULATING ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1987-12-08 | — | — | US | disclosed |
| US-4640911-A | IMMUNOSTIMULANTS, VIRICIDES SUCH AS HERPES SIMPLEX | CIBA-GEIGY CORPORATION (US) | 1987-02-03 | — | — | US | disclosed |