Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897255 | 0.84 | ALDH1A1 (0.45) | AKR1C3AKR1C2MAPK1SLC6A3ALDH1A1 | |
| SCHEMBL11009286 | 0.83 | AKR1C3 (0.36) | AKR1C3AKR1C2S1PR1MEN1PKM | |
| SCHEMBL1104688 | 0.77 | LMNA (0.52) | AKR1C3AKR1C2S1PR1MEN1PKM | |
| SCHEMBL9865412 | 0.76 | MDM2 (0.40) | MEN1KMT2ASLC6A3LMNAKDM4E | |
| SCHEMBL14401158 | 0.75 | TRPV4 (0.46) | AKR1C3AKR1C2S1PR1MEN1PKM | |
| SCHEMBL13075535 | 0.74 | ADRB2 (0.52) | AKR1C3AKR1C2S1PR1MEN1PKM | |
| SCHEMBL16953624 | 0.74 | S1PR1 (0.41) | AKR1C3AKR1C2S1PR1MEN1PKM | |
| SCHEMBL17084122 | 0.74 | S1PR1 (0.41) | AKR1C3AKR1C2S1PR1MEN1PKM | |
| SCHEMBL17084190 | 0.74 | S1PR1 (0.41) | AKR1C3AKR1C2S1PR1MEN1PKM | |
| SCHEMBL8185537 | 0.74 | ADRB2 (0.52) | AKR1C3AKR1C2S1PR1MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661986-A4 | BRAIN-ENHANCED DELIVERY OF NEUROACTIVE PEPTIDES BY SEQUENTIAL METABOLISM. | UNIV FLORIDA (US) | 1997-04-23 | — | — | EP | disclosed |
| EP-0661986-A1 | BRAIN-ENHANCED DELIVERY OF NEUROACTIVE PEPTIDES BY SEQUENTIAL METABOLISM | UNIVERSITY OF FLORIDA (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994006450-A1 | BRAIN-ENHANCED DELIVERY OF NEUROACTIVE PEPTIDES BY SEQUENTIAL METABOLISM | UNIVERSTIY OF FLORIDA (US) | 1994-03-31 | — | — | WO | disclosed |