SCHEMBL10797484

SCHEMBL10797484

Cc1ccc(NC(=N)N)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 3/20 0.39
ALDH1A1 P00352 5/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
HTT P42858 1/20 0.39
WDR5 P61964 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 2/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
MAPT P10636 3/20 0.33
FABP3 P05413 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
GAA P10253 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6268723 0.88 HPGD (0.39) FABP4ALDH1A1LMNATP53HTT
SCHEMBL7617157 0.79 PLAU (0.36) FABP4ALDH1A1HTTWDR5KDM4E
SCHEMBL2254824 0.78 SLC1A3 (0.55) ALDH1A1HTTWDR5KDM4ESLC1A3
SCHEMBL6263678 0.77 HDAC7 (0.45) ALDH1A1LMNAHTTMAPTMEN1
SCHEMBL2994615 0.76 SIGMAR1 (0.44) FABP4ALDH1A1HTTWDR5HPGD
SCHEMBL6265251 0.75 KIF11 (0.39) ALDH1A1LMNATP53HTTWDR5
SCHEMBL22391489 0.74 MAPT (0.48) FABP4ALDH1A1LMNAHTTHPGD
SCHEMBL467514 0.74 NPC1 (0.57) ALDH1A1LMNAHTTKDM4EHPGD
SCHEMBL29401646 0.74 NPC1 (0.57) ALDH1A1LMNAHTTKDM4EHPGD
Hydrochloric Acid SCHEMBL11234820 0.72 NPC1 (0.55) ALDH1A1HPGDMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4650740-A DIAZONIUM SALT AND COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1987-03-17 US claimed
US-4650740-A DIAZONIUM SALT AND COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1987-03-17 US disclosed