Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115195 | 0.85 | SIGMAR1 (0.57) | SIGMAR1ALDH1A1MEN1CYP2C9HPGD | |
| SCHEMBL7617157 | 0.79 | PLAU (0.36) | SIGMAR1PLAUPLATALDH1A1HPGD | |
| SCHEMBL10785558 | 0.79 | ALDH1A1 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL10797484 | 0.76 | FABP4 (0.39) | SIGMAR1ALDH1A1MEN1CYP2C9HPGD | |
| SCHEMBL29116511 | 0.76 | MAOA (0.61) | ALDH1A1CYP2C9HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5016493 | 0.76 | ALDH1A1 (0.41) | SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5563589 | 0.75 | MAOA (0.55) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5560042 | 0.75 | MAOA (0.64) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL2002382 | 0.74 | GAA (0.50) | SIGMAR1ALDH1A1KMT2ASMN1; SMN2PRSS1 | |
| SCHEMBL6263678 | 0.73 | HDAC7 (0.45) | SIGMAR1PLAUPLATALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084547-B2 | Methods for producing rubber mixtures | LANXESS DEUTSCHLAND GMBH (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100197829-A1 | METHODS FOR PRODUCING RUBBER MIXTURES | LANXESS DEUTSCHLAND GMBH (DE) | 2010-08-05 | — | — | US | disclosed |