SCHEMBL10797604

SCHEMBL10797604

CO/N=C\c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
SRC P12931 3/20 0.50
PLA2G7 Q13093 1/20 0.48
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
FAAH O00519 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
NOX1 Q9Y5S8 1/20 0.41
TRPA1 O75762 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113602 1.00 LMNA (0.52) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL113601 1.00 LMNA (0.52) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL13397720 0.87 SRC (0.61) LMNASRCPPARGPPARANPC1
SCHEMBL14572074 0.87 SRC (0.48) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL28173018 0.87 SRC (0.48) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL14572076 0.83 NPC1 (0.55) LMNAL3MBTL1SRCPPARGPPARA
Propane SCHEMBL11032480 0.82 PPARG (0.41) LMNAL3MBTL1SRCPLA2G7PPARG
Propene SCHEMBL11100982 0.82 SRC (0.41) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL2901541 0.81 LMNA (0.48) LMNAL3MBTL1PLA2G7NPC1RAB9A
SCHEMBL28484755 0.81 LMNA (0.48) LMNAL3MBTL1PLA2G7NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4696964-A HEAT RESISTANCE, OXIDATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1987-09-29 US disclosed