Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 3/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10797604 | 1.00 | LMNA (0.52) | LMNAL3MBTL1SRCPLA2G7PPARG | |
| SCHEMBL113601 | 1.00 | LMNA (0.52) | LMNAL3MBTL1SRCPLA2G7PPARG | |
| SCHEMBL13397720 | 0.87 | SRC (0.61) | LMNASRCPPARGPPARANPC1 | |
| SCHEMBL14572074 | 0.87 | SRC (0.48) | LMNAL3MBTL1SRCPLA2G7PPARG | |
| SCHEMBL28173018 | 0.87 | SRC (0.48) | LMNAL3MBTL1SRCPLA2G7PPARG | |
| SCHEMBL14572076 | 0.83 | NPC1 (0.55) | LMNAL3MBTL1SRCPPARGPPARA | |
| Propane SCHEMBL11032480 | 0.82 | PPARG (0.41) | LMNAL3MBTL1SRCPLA2G7PPARG | |
| Propene SCHEMBL11100982 | 0.82 | SRC (0.41) | LMNAL3MBTL1SRCPLA2G7PPARG | |
| SCHEMBL2901541 | 0.81 | LMNA (0.48) | LMNAL3MBTL1PLA2G7NPC1RAB9A | |
| SCHEMBL28484755 | 0.81 | LMNA (0.48) | LMNAL3MBTL1PLA2G7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 795 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3624849-A1 | COMBINATION THERAPY USING ASCOCHLORIN DERIVATIVE | Hoshino, Tatsuo (JP) | 2020-03-25 | — | — | EP | claimed |
| WO-2018212363-A1 | COMBINATION THERAPY USING ASCOCHLORIN DERIVATIVE | NRL PHARMA, INC. (JP) | 2018-11-22 | — | — | WO | claimed |
| US-9371262-B2 | One-step intermolecular electrocyclic rearrangement process | GIVAUDAN S.A. (CH) | 2016-06-21 | — | — | US | claimed |
| CN-103467300-B | A kind of synthetic method of o-nitrobenzaldehyde compounds | JIANG University OF TECHNOLOGY (CN) | 2016-02-24 | — | — | CN | claimed |
| US-20140288326-A1 | NOVEL PROCESS | GIVAUDAN S.A. (CH) | 2014-09-25 | — | — | US | claimed |
| CN-103889969-A | Novel process | GIVAUDAN SA | 2014-06-25 | — | — | CN | claimed |
| CN-103467300-A | Synthesizing method for o-nitrobenzaldehyde compound | UNIV ZHEJIANG TECHNOLOGY | 2013-12-25 | — | — | CN | claimed |
| WO-2013060011-A1 | NOVEL PROCESS | GIVAUDAN SA (CH) | 2013-05-02 | — | — | WO | claimed |
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| EP-1737823-A2 | NOVEL ALKYNE COMPOUNDS WITH AN MCH-ANTAGONISTIC ACTION AND MEDICAMENTS COMPRISING SAID COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2007-01-03 | — | — | EP | claimed |
| WO-2005103002-A2 | NOVEL ALKYNE COMPOUNDS WITH AN MCH-ANTAGONISTIC ACTION AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-03 | — | — | WO | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| CN-1349416-A | Contraceptive compositions contaiing indoline derivatives and progestational agents | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | claimed |
| EP-0030702-B1 | PROPIONIC-ACID ESTERS, PREPARATION OF THESE COMPOUNDS, HERBICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, USE OF SUCH COMPOUNDS AND AGENTS AS HERBICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-08-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | LMNA 4552/4885L3MBTL1 3559/4885SRC 3829/4885 |
| US-20140288326-A1 | NOVEL PROCESS | COASY, ADH1C, AKR1C2 | LMNA 517/4885L3MBTL1 3962/4885SRC 4546/4885 |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | LMNA 4062/4885L3MBTL1 2013/4885SRC 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.