SCHEMBL113601

SCHEMBL113601

CO/N=C/c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
SRC P12931 3/20 0.50
PLA2G7 Q13093 1/20 0.48
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
FAAH O00519 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
NOX1 Q9Y5S8 1/20 0.41
TRPA1 O75762 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113602 1.00 LMNA (0.52) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL10797604 1.00 LMNA (0.52) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL13397720 0.87 SRC (0.61) LMNASRCPPARGPPARANPC1
SCHEMBL14572074 0.87 SRC (0.48) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL28173018 0.87 SRC (0.48) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL14572076 0.83 NPC1 (0.55) LMNAL3MBTL1SRCPPARGPPARA
Propane SCHEMBL11032480 0.82 PPARG (0.41) LMNAL3MBTL1SRCPLA2G7PPARG
Propene SCHEMBL11100982 0.82 SRC (0.41) LMNAL3MBTL1SRCPLA2G7PPARG
SCHEMBL2901541 0.81 LMNA (0.48) LMNAL3MBTL1PLA2G7NPC1RAB9A
SCHEMBL28484755 0.81 LMNA (0.48) LMNAL3MBTL1PLA2G7NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 747 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-12637672-B2 Oligonucleotide compositions and methods thereof WAVE LIFE SCIENCES LTD. (SG) 2026-05-26 US disclosed
US-12403156-B2 Oligonucleotides, compositions and methods thereof WAVE LIFE SCIENCES LTD. (SG) 2025-09-02 US disclosed
WO-2025151874-A1 INDOLE ALKALOID ANTIPLASMODIAL AGENTS AND PREPARATION THEREOF UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2025-07-17 WO disclosed
US-12083186-B2 Methods for assembling scavenging particles NANOTICS, LLC (US) 2024-09-10 US disclosed
US-20240269319-A1 METHODS FOR ASSEMBLING SCAVENGING PARTICLES NANOTICS, LLC 2024-08-15 US disclosed
WO-2024148274-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2024-07-11 WO disclosed
WO-2024147060-A1 NOVEL IONIZABLE LIPID COMPOUNDS FOR NUCLEIC ACID DELIVERY CELON PHARMA S.A. (PL) 2024-07-11 WO disclosed
WO-2024145281-A1 BIODEGRADABLE LIPIDS AND FORMULATIONS FOR INTRAMUSCULAR, IN VITRO, AND EX VIVO TRANSFECTION OF MRNA MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-07-04 WO disclosed
US-20070149551-A1 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE GYPSER ANDREAS 2007-06-28 US disclosed
US-20070066639-A1 Oxime substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2007-03-22 US disclosed
US-20070066639-A1 Oxime substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2007-03-22 US disclosed
WO-2007013965-A2 SYNTHESIS OF SCABRONINES AND ANALOGUES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2007-02-01 WO disclosed
EP-1212327-B8 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS ABBOTT GMBH & CO KG (DE) 2004-02-25 EP disclosed
EP-1212327-A2 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-06-12 EP disclosed
WO-2001019829-A2 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-22 WO disclosed
EP-0369334-A2 1-Aminoalkyl-3-oxysubstituted-4-aryl-1,3,4,5-tetrahydro-2H-1,3-benzodiazepine-2-ones, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1990-05-23 EP disclosed
US-4908360-A Hypotensive agents HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1990-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149551-A1 5-PHENYLPYRIMIDINES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE CBR1, CBR3, NTPCR LMNA 2453/4885L3MBTL1 2590/4885SRC 2465/4885
US-12403156-B2 Oligonucleotides, compositions and methods thereof TLR9, RNGTT, NT5C3B LMNA 3612/4885L3MBTL1 722/4885SRC 1353/4885
US-20070066639-A1 Oxime substituted imidazoquinolines IFNG, IRF3, IL2 LMNA 4420/4885L3MBTL1 3727/4885SRC 1497/4885
US-12637672-B2 Oligonucleotide compositions and methods thereof UPF1, SMN1; SMN2, RNGTT LMNA 870/4885L3MBTL1 131/4885SRC 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.