Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741010 | 0.87 | EBP (0.45) | ESR1ESR2EBPSIGMAR1LTA4H | |
| SCHEMBL10877318 | 0.86 | EBP (0.57) | ESR1EBPSIGMAR1LTA4HMCHR1 | |
| SCHEMBL10876584 | 0.79 | ESR1 (0.40) | ESR1ESR2EBPSIGMAR1LTA4H | |
| SCHEMBL10795345 | 0.78 | ESR1 (0.48) | ESR1ESR2EBPSIGMAR1LTA4H | |
| SCHEMBL10794219 | 0.78 | EBP (0.53) | ESR1ESR2EBPSIGMAR1LTA4H | |
| SCHEMBL10794929 | 0.78 | LTA4H (0.48) | ESR1ESR2EBPSIGMAR1LTA4H | |
| SCHEMBL10799703 | 0.78 | MEN1 (0.51) | ESR1ESR2LTA4HMCHR1CHRNB2 | |
| SCHEMBL10786833 | 0.78 | MAOB (0.44) | ESR1CHRNB2CHRNA4 | |
| SCHEMBL10799716 | 0.75 | LTA4H (0.44) | ESR1ESR2LTA4HMCHR1CHRNB2 | |
| SCHEMBL10795277 | 0.75 | LTA4H (0.44) | ESR1ESR2EBPSIGMAR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114410-B1 | SUBSTITUTED ALPHA-(ETHYL)-ALPHA-(PHENYL)-(OMEGA-(DIALKYLAMINO)-ALKOXY)-BENZYL ALCOHOLS, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION, AS WELL AS MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-05-14 | — | — | EP | claimed |
| US-4645779-A | TREATMENT OF ACUTE ETHANOLIC INTOXICATION | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-02-24 | — | — | US | disclosed |
| EP-0114410-B1 | SUBSTITUTED ALPHA-(ETHYL)-ALPHA-(PHENYL)-(OMEGA-(DIALKYLAMINO)-ALKOXY)-BENZYL ALCOHOLS, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION, AS WELL AS MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-05-14 | — | — | EP | disclosed |
| EP-0114410-A1 | Substituted alpha-(ethyl)-alpha-(phenyl)-(omega-(dialkylamino)-alkoxy)-benzyl alcohols, their acid addition salts and quaternary salts, process for their preparation, as well as medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-08-01 | — | — | EP | disclosed |