Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 4/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741010 | 0.89 | EBP (0.45) | EBPSIGMAR1ACHEHRH3CYP2D6 | |
| SCHEMBL10797608 | 0.86 | ESR1 (0.43) | EBPSIGMAR1ACHELTA4HKCNH2 | |
| SCHEMBL10896552 | 0.83 | EBP (0.49) | EBPSIGMAR1ACHEHRH3MAOB | |
| SCHEMBL10356744 | 0.78 | CYP2D6 (0.58) | EBPSIGMAR1ACHEHRH3HTT | |
| SCHEMBL10878286 | 0.77 | EBP (0.72) | EBPSIGMAR1ACHEHRH3HTT | |
| SCHEMBL10880656 | 0.77 | EBP (0.55) | EBPSIGMAR1HRH3MAOBHTT | |
| SCHEMBL10879788 | 0.77 | KMT2A (0.53) | EBPSIGMAR1HRH3HTTCYP2D6 | |
| SCHEMBL10786833 | 0.77 | MAOB (0.44) | MAOBCYP1A2CYP2C19KMT2AMAPT | |
| SCHEMBL10890654 | 0.75 | ESR1 (0.46) | ACHEESR1SLC6A2SLC6A4HTR6 | |
| SCHEMBL7753432 | 0.75 | SIGMAR1 (0.79) | EBPSIGMAR1ACHEHRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115080-B1 | (OMEGA-(DIETHYLAMINO)-ALKOXY)-ALPHA-(ETHYL)-BENZHYDROL DERIVATIVES, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-16 | — | — | EP | claimed |
| US-4605672-A | ANTIDEPRESSANTS; TREATMENT OF ETHANOLIC INTOXICATION; LOW TOXICITY AND FEW SIDE EFFECTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1986-08-12 | — | — | US | disclosed |