Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877318 | 0.89 | EBP (0.57) | EBPSIGMAR1KDM4EPOLBACHE | |
| SCHEMBL10797608 | 0.87 | ESR1 (0.43) | EBPSIGMAR1ACHEESR1LTA4H | |
| SCHEMBL10786833 | 0.78 | MAOB (0.44) | KDM4EESR1MAPTMEN1CYP1A2 | |
| SCHEMBL10743204 | 0.77 | KDM4E (0.52) | EBPSIGMAR1KDM4EPOLBALDH1A1 | |
| SCHEMBL10746230 | 0.77 | EBP (0.56) | EBPSIGMAR1KDM4EPOLBALDH1A1 | |
| SCHEMBL10738058 | 0.77 | MEN1 (0.53) | EBPSIGMAR1KDM4EPOLBALDH1A1 | |
| SCHEMBL10890654 | 0.76 | ESR1 (0.46) | ALDH1A1ACHEESR1CYP3A4CNR1 | |
| SCHEMBL10889760 | 0.74 | MEN1 (0.43) | SIGMAR1POLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10856859 | 0.74 | PDE10A (0.38) | SMN1; SMN2MAPTMEN1NPC1TP53 | |
| SCHEMBL10741572 | 0.73 | KDM4E (0.53) | EBPSIGMAR1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115205-B1 | AMINOETHOXYBENZYLALCOHOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1986-10-29 | — | — | EP | claimed |
| EP-0115205-A1 | Aminoethoxybenzylalcohol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-08 | — | — | EP | claimed |
| US-4645774-A | POLYSUBSTRATE MONOOXYGENASE ENZYME INDUCER | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-02-24 | — | — | US | disclosed |
| EP-0115205-A1 | Aminoethoxybenzylalcohol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-08 | — | — | EP | disclosed |