Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.54 |
| ▸ | USP2 | O75604 | 7/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
| ▸ | AR | P10275 | 4/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10427840 | 1.00 | PGR (0.54) | PGRCYP3A4USP2NR3C1ADORA3 | |
| SCHEMBL10798059 | 0.95 | PGR (0.49) | PGRCYP3A4USP2NR3C1ADORA3 | |
| SCHEMBL10427774 | 0.95 | PGR (0.49) | PGRCYP3A4USP2NR3C1ADORA3 | |
| SCHEMBL10804061 | 0.91 | CYP3A4 (0.53) | PGRCYP3A4USP2NR3C1ADORA3 | |
| SCHEMBL10427801 | 0.91 | CYP3A4 (0.53) | PGRCYP3A4USP2NR3C1ADORA3 | |
| SCHEMBL10623139 | 0.90 | NR3C1 (0.42) | PGRCYP3A4USP2NR3C1ADORA3 | |
| SCHEMBL10623130 | 0.90 | NR3C1 (0.42) | PGRCYP3A4USP2NR3C1ADORA3 | |
| SCHEMBL10427810 | 0.89 | PGR (0.61) | PGRCYP3A4USP2NR3C1ADORA3 | |
| SCHEMBL10427809 | 0.89 | PGR (0.61) | PGRCYP3A4USP2NR3C1ADORA3 | |
| SCHEMBL10427813 | 0.86 | PGR (0.50) | PGRCYP3A4USP2NR3C1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4701451-A | Novel 6,16-dimethylcorticoids their preparation and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-10-20 | — | — | US | disclosed |
| US-4555507-A | Novel 6, 16-dimethylcorticoids, their preparation and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | disclosed |