Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798218 | 0.87 | MAPT (0.46) | NPC1GAARAB9AMAPTMEN1 | |
| SCHEMBL10793193 | 0.83 | PTGS2 (0.47) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL10794436 | 0.78 | NPC1 (0.39) | NPC1GAARAB9AMAPTMEN1 | |
| SCHEMBL12767841 | 0.78 | NPC1 (0.52) | NPC1GAARAB9AMAPTMEN1 | |
| SCHEMBL10792190 | 0.77 | ACACB (0.48) | ALDH1A1LMNATSHRHPGD | |
| SCHEMBL16954387 | 0.75 | MAPT (0.45) | NPC1GAARAB9AMAPTMEN1 | |
| SCHEMBL6246000 | 0.74 | MAPT (0.57) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL1202354 | 0.74 | GAA (0.42) | NPC1GAARAB9AMAPTMEN1 | |
| SCHEMBL10920745 | 0.74 | ALDH1A1 (0.52) | ALDH1A1LMNATSHRL3MBTL1MAPK1 | |
| SCHEMBL16954938 | 0.72 | MAPT (0.42) | NPC1GAARAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668815-A | FROM ACYL HALIDE AND ALCOHOL WITH TIRPLE BOND | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-05-26 | — | — | US | disclosed |