Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799731 | 0.74 | CYP19A1 (0.48) | MAPTPDE4DKMT2AHSP90AA1CYP19A1 | |
| SCHEMBL5440264 | 0.73 | MAPT (0.49) | MAPTPDE4DKMT2AHSP90AA1CYP19A1 | |
| SCHEMBL10900677 | 0.71 | MAPT (0.44) | MAPTPDE4DKMT2AHSP90AA1CYP19A1 | |
| SCHEMBL2754295 | 0.71 | MAPT (0.44) | MAPTPDE4DKMT2AHSP90AA1CYP19A1 | |
| SCHEMBL21681423 | 0.70 | KMT2A (0.34) | MAPTPDE4DKMT2AHSP90AA1CYP19A1 | |
| SCHEMBL21681482 | 0.70 | MAPT (0.38) | MAPTPDE4DKMT2AHSP90AA1CYP19A1 | |
| SCHEMBL9748570 | 0.69 | MAPT (0.63) | MAPTPDE4DKMT2AHSP90AA1CYP19A1 | |
| SCHEMBL6319766 | 0.69 | MAPT (0.44) | MAPTKMT2AHSP90AA1CYP19A1 | |
| SCHEMBL22372311 | 0.68 | CES2 (0.52) | MAPTCES2CES1KMT2ADPP8 | |
| SCHEMBL11131956 | 0.68 | JAK2 (0.39) | MAPTKMT2AHSP90AA1CYP19A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122693-B1 | ANTIFUNGAL DI(AZOLYL)PROPANOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-08 | — | — | EP | disclosed |
| US-4625036-A | Antifungal azole compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-25 | — | — | US | disclosed |
| EP-0122693-A1 | Antifungal di(azolyl)propanol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-24 | — | — | EP | disclosed |