SCHEMBL9501074

SCHEMBL9501074

C=CCOc1nc(OCC=C)nc(OCCO)n1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
SLC29A1 Q99808 1/20 0.39
PDE10A Q9Y233 1/20 0.32
ALDH1A1 P00352 1/20 0.30
RECQL P46063 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10798317 0.87 MAPK1 (0.50) MAPTMAPK1
SCHEMBL23181 0.84 MAPK1 (0.55) MAPTMAPK1ALDH1A1TSHR
SCHEMBL10815003 0.83 MAPT (0.47) MAPTMAPK1ALDH1A1TSHR
Hydrogen Sulfide SCHEMBL20395887 0.82 MAPK1 (0.53) MAPTMAPK1ALDH1A1TSHR
SCHEMBL600149 0.82 SLC29A1 (0.48) MAPK1SLC29A1PDE10AALDH1A1RECQL
SCHEMBL10961266 0.81 MAPT (0.46) MAPTMAPK1ALDH1A1TSHR
SCHEMBL1065177 0.81 MAPT (0.46) MAPTMAPK1TSHR
SCHEMBL11182506 0.81 MAPT (0.46) MAPTMAPK1ALDH1A1TSHR
SCHEMBL10960929 0.81 MAPT (0.46) MAPTMAPK1
SCHEMBL6124831 0.79 MAPT (0.44) MAPTMAPK1PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0375079-B1 ALKENYLPHOXYLIMIDE MODIFIED POLYIMIDE Technochemie GmbH - Verfahrenstechnik (DE) 1993-06-09 EP disclosed
US-5120824-A Molding materials based on unsaturated monomers containing imide groups; engineering thermoplastics; toughness; heat resistance TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1992-06-09 US disclosed
EP-0469684-A1 Polyimide compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-02-05 EP disclosed
US-4981934-A Curable composition comprising bis-imide and bis-(alkenyl phenol) TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1991-01-01 US disclosed
EP-0375079-A2 Alkenylphoxylimide modified polyimide Technochemie GmbH - Verfahrenstechnik (DE) 1990-06-27 EP disclosed
EP-0355926-A2 Alkenyl-modified polyimides Technochemie GmbH - Verfahrenstechnik (DE) 1990-02-28 EP disclosed
EP-0091778-B1 IMPROVEMENT IN OR RELATING TO AROMATIC POLYAMIDE FILM TEIJIN LIMITED (JP) 1987-12-09 EP disclosed
US-4539393-A Dimensionally stable poly-m-phenylene isophthalamide film TEIJIN LIMITED (JP) 1985-09-03 US disclosed
EP-0091778-A2 Improvement in or relating to aromatic polyamide film TEIJIN LIMITED (JP) 1983-10-19 EP disclosed
US-4064193-A Heat-resistant polymers based on polyamines and oligomers possessing imide groups with unsaturated polyester RHONE-POULENC S.A. (FR) 1977-12-20 US disclosed
US-4035345-A Thermosetting bis-imide compositions RHONE-POULENC S.A. (FR) 1977-07-12 US disclosed
US-4005154-A Curing 1,2-epoxy with prepolymer based on polyamines and oligomers possessing imide groups RHONE-POULENC S.A. (FR) 1977-01-25 US disclosed