Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23932789 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TDP1MEN1MAPT | |
| SCHEMBL30776717 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TDP1MEN1MAPT | |
| SCHEMBL10722001 | 0.79 | ACP3 (0.40) | ALDH1A1CYP3A4KDM4EMAPK1ACP3 | |
| SCHEMBL9355693 | 0.76 | CA12 (0.52) | ALDH1A1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL29633722 | 0.75 | ALOX15 (0.48) | ALDH1A1CYP3A4TDP1MAPTTHRB | |
| SCHEMBL17607326 | 0.75 | ALOX15 (0.48) | ALDH1A1CYP3A4TDP1MAPTTHRB | |
| SCHEMBL1708793 | 0.74 | TDP1 (0.42) | ALDH1A1CYP3A4TDP1MEN1MAPT | |
| SCHEMBL11218408 | 0.74 | ACP3 (0.39) | ALDH1A1CYP3A4KDM4EMAPK1ACP3 | |
| SCHEMBL10721677 | 0.74 | KDM4E (0.51) | ALDH1A1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL8772914 | 0.72 | CA2 (0.39) | ALDH1A1TDP1KDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245190-A1 | CATALYTIC DE-CROSSLINKING OF SAMPLES FOR IN SITU ANALYSIS | 10X GENOMICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| US-4642240-A | LOW CALORIE SWEETENERS | GENERAL FOODS CORPORATION (US) | 1987-02-10 | — | — | US | disclosed |