SCHEMBL107988

SCHEMBL107988

Cc1cc(N(CCO)CCO)ccc1N=Nc1ccc(N)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.61
KMT2A Q03164 10/20 0.61
RAB9A P51151 9/20 0.61
MEN1 O00255 9/20 0.61
NPC1 O15118 8/20 0.61
TDP1 Q9NUW8 8/20 0.61
MAPK1 P28482 7/20 0.61
L3MBTL1 Q9Y468 5/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
POLB P06746 2/20 0.61
LMNA P02545 2/20 0.61
MMP14 P50281 1/20 0.61
PSMD14 O00487 2/20 0.43
MITF O75030 1/20 0.43
PKM P14618 3/20 0.40
HTT P42858 2/20 0.40
GAA P10253 1/20 0.40
MCL1 Q07820 1/20 0.40
ATM Q13315 3/20 0.38
ATIC P31939 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29596363 1.00 MAPT (0.61) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL107987 1.00 MAPT (0.61) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL8406566 0.92 MAPT (0.54) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL14174536 0.88 RAB9A (0.47) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL9023308 0.85 KMT2A (0.49) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL9022928 0.85 KMT2A (0.49) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL8250902 0.84 MAPT (0.58) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL7761808 0.84 KMT2A (0.43) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL9022512 0.84 KMT2A (0.43) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL9022499 0.84 KMT2A (0.42) MAPTKMT2ARAB9AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3034066-A1 Hair colouring compositions Unilever PLC (GB) 2016-06-22 EP claimed
EP-0739622-B1 Hair dye composition WELLA AG (DE) 2001-06-20 EP claimed
US-5637115-A Oxidation hair dye compositions containing developers, couplers, and AZO dyes WELLA AKTIENGESELLSCHAT (DE) 1997-06-10 US claimed
EP-0739622-A1 Hair dye composition Wella Aktiengesellschaft (DE) 1996-10-30 EP claimed
EP-0480829-B1 Hair dyeing composition containing anthraquinones OREAL (FR) 1994-04-06 EP claimed
US-5226924-A 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM L'OREAL (FR) 1993-07-13 US claimed
EP-0480829-A1 Hair dyeing composition containing anthraquinones L'OREAL (FR) 1992-04-15 EP claimed
US-4886517-A GOOD WATER SOLUBILITY L'OREAL (FR) 1989-12-12 US claimed
CN-118621464-A Electrostatic spinning solution, artificial hair fiber, and preparation method and application thereof 香港理工大学 2024-09-10 CN disclosed
EP-3229918-B1 COMPOSITION AND PROCEDURE FOR TREATING KERATINIC FIBERS WITH FLASH EVAPORATION HENKEL AG & CO KGAA (DE) 2024-03-13 EP disclosed
WO-2023180560-A1 COMPOSITION FOR ENHANCING KERATIN FIBERS WELLA GERMANY GMBH (DE) 2023-09-28 WO disclosed
WO-2023067176-A1 WATER REDUCED COMPACT SHAMPOO COMPOSITION WELLA GERMANY GMBH (DE) 2023-04-27 WO disclosed
WO-2023066502-A1 WATER REDUCED COMPACT CONDITIONER COMPOSITION WELLA GERMANY GMBH (DE) 2023-04-27 WO disclosed
WO-2023067173-A1 WATER REDUCED COMPACT CONDITIONER COMPOSITION WELLA GERMANY GMBH (DE) 2023-04-27 WO disclosed
EP-0480829-A1 Hair dyeing composition containing anthraquinones L'OREAL (FR) 1992-04-15 EP disclosed
US-5015769-A Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination L'OREAL (FR) 1991-05-14 US disclosed
US-4904276-A Nitroaminophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate nitroaminobenzenes and their use in dyeing keratinous fibres L'OREAL (FR) 1990-02-27 US disclosed
US-4886517-A GOOD WATER SOLUBILITY L'OREAL (FR) 1989-12-12 US disclosed
US-4749379-A HAIR DYES L'OREAL (FR) 1988-06-07 US disclosed
US-4740622-A 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols L'OREAL (FR) 1988-04-26 US disclosed