Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.61 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 9/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MMP14 | P50281 | 1/20 | 0.61 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | ATIC | P31939 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107988 | 1.00 | MAPT (0.61) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL29596363 | 1.00 | MAPT (0.61) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL8406566 | 0.92 | MAPT (0.54) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL14174536 | 0.88 | RAB9A (0.47) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9023308 | 0.85 | KMT2A (0.49) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9022928 | 0.85 | KMT2A (0.49) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL8250902 | 0.84 | MAPT (0.58) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL7761808 | 0.84 | KMT2A (0.43) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9022512 | 0.84 | KMT2A (0.43) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9022499 | 0.84 | KMT2A (0.42) | MAPTKMT2ARAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229918-B1 | COMPOSITION AND PROCEDURE FOR TREATING KERATINIC FIBERS WITH FLASH EVAPORATION | HENKEL AG & CO KGAA (DE) | 2024-03-13 | — | — | EP | disclosed |
| US-20230346669-A1 | PROCESS FOR DYEING KERATIN FIBERS USING A DIRECT DYE AND A SACCHARINATE SALT AND COMPOSITION COMPRISING THEM | L'OREAL (FR) | 2023-11-02 | — | — | US | disclosed |
| US-20230346669-A1 | PROCESS FOR DYEING KERATIN FIBERS USING A DIRECT DYE AND A SACCHARINATE SALT AND COMPOSITION COMPRISING THEM | L'OREAL (FR) | 2023-11-02 | — | — | US | disclosed |
| US-20230310294-A1 | COMPOSITION FOR SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBERS, COMPRISING A PARTICULAR HETEROCYCLIC SALT, AND PROCESS USING THIS COMPOSITION | L'OREAL (FR) | 2023-10-05 | — | — | US | disclosed |
| US-20230310294-A1 | COMPOSITION FOR SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBERS, COMPRISING A PARTICULAR HETEROCYCLIC SALT, AND PROCESS USING THIS COMPOSITION | L'OREAL (FR) | 2023-10-05 | — | — | US | disclosed |
| US-11672747-B2 | Process for dyeing keratin materials using a direct dye and an aliphatic ammonium salt, and composition comprising same | L'OREAL (FR) | 2023-06-13 | — | — | US | disclosed |
| US-11672747-B2 | Process for dyeing keratin materials using a direct dye and an aliphatic ammonium salt, and composition comprising same | L'OREAL (FR) | 2023-06-13 | — | — | US | disclosed |
| US-20220183944-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME | L'OREAL (FR) | 2022-06-16 | — | — | US | disclosed |
| US-20210115489-A1 | NOVEL MEDIATOR | KIKKOMAN CORPORATION (JP) | 2021-04-22 | — | — | US | disclosed |
| EP-2263642-B1 | Colouring bleaches | HENKEL AG & CO KGAA (DE) | 2020-04-15 | — | — | EP | disclosed |
| EP-0877593-A1 | AGENT FOR DYEING AND DECOLORIZING FIBERS | Wella Aktiengesellschaft (DE) | 1998-11-18 | — | — | EP | disclosed |
| WO-1998023247-A1 | AGENT FOR DYEING AND DECOLORIZING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |
| WO-1998022078-A1 | AGENTS FOR DYING AND DECOLORIZING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-05-28 | — | — | WO | disclosed |
| EP-0688767-A1 | 5-mercapto-2-nitro paraphenylenediamine compounds and hair dye compositions containing same | Bristol-Myers Squibb Company (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5468256-A | Solvent, anionic, cationic or nonionic surfactant with monoazo dye | WELLA AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | disclosed |
| US-5409502-A | Acid resistance | WELLA AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | disclosed |
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-4904276-A | Nitroaminophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate nitroaminobenzenes and their use in dyeing keratinous fibres | L'OREAL (FR) | 1990-02-27 | — | — | US | disclosed |
| US-4749379-A | HAIR DYES | L'OREAL (FR) | 1988-06-07 | — | — | US | disclosed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115489-A1 | NOVEL MEDIATOR | MPO, EPX, LPO | MAPT 4015/4885KMT2A 3104/4885RAB9A 3686/4885 |
| US-20230346669-A1 | PROCESS FOR DYEING KERATIN FIBERS USING A DIRECT DYE AND A SACCHARINATE SALT AND COMPOSITION COMPRISING THEM | KRT18, DSG1, KRTCAP2 | MAPT 355/4885KMT2A 1884/4885RAB9A 3248/4885 |
| US-20230310294-A1 | COMPOSITION FOR SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBERS, COMPRISING A PARTICULAR HETEROCYCLIC SALT, AND PROCESS USING THIS COMPOSITION | KRT18, KAT2B, SPIN2B | MAPT 1259/4885KMT2A 516/4885RAB9A 1928/4885 |
| US-11672747-B2 | Process for dyeing keratin materials using a direct dye and an aliphatic ammonium salt, and composition comprising same | KRT18, MARK1, IK | MAPT 465/4885KMT2A 684/4885RAB9A 3926/4885 |
| US-20220183944-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME | KRT18, MARK1, IK | MAPT 465/4885KMT2A 684/4885RAB9A 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.