Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712417 | 0.79 | ALDH1A1 (0.52) | ALDH1A1NR1H2NR1H3TDP1TSHR | |
| SCHEMBL15473032 | 0.74 | ALDH1A1 (0.52) | ALDH1A1NR1H2NR1H3TDP1TSHR | |
| SCHEMBL30423535 | 0.74 | ALDH1A1 (0.52) | ALDH1A1NR1H2NR1H3TDP1TSHR | |
| SCHEMBL10798212 | 0.73 | ALDH1A1 (0.46) | ALDH1A1NR1H2NR1H3TDP1TSHR | |
| SCHEMBL7649599 | 0.73 | ALDH1A1 (0.58) | ALDH1A1NR1H2NR1H3TDP1TSHR | |
| SCHEMBL141101 | 0.73 | ALDH1A1 (0.58) | ALDH1A1NR1H2NR1H3TDP1TSHR | |
| SCHEMBL27193611 | 0.73 | ALDH1A1 (0.58) | ALDH1A1NR1H2NR1H3TDP1TSHR | |
| SCHEMBL9488658 | 0.70 | ALDH1A1 (0.52) | ALDH1A1NR1H2NR1H3TDP1TSHR | |
| SCHEMBL899595 | 0.70 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRHDAC8TRPA1 | |
| SCHEMBL8758684 | 0.70 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRHDAC8TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4636454-A | STYRENE VINYLDIMETHYLSILANE POLYMER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1987-01-13 | — | — | US | claimed |
| US-4636454-A | STYRENE VINYLDIMETHYLSILANE POLYMER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1987-01-13 | — | — | US | disclosed |