SCHEMBL7712417

SCHEMBL7712417

C=Cc1ccc([Si](C)(C)C=C)cc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
NR1H2 P55055 1/20 0.50
NR1H3 Q13133 1/20 0.50
TSHR P16473 1/20 0.40
HDAC8 Q9BY41 3/20 0.39
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678612 0.87 NR1H2 (0.59) NR1H2NR1H3
SCHEMBL7630321 0.82 NR1H2 (0.47) ALDH1A1NR1H2NR1H3
SCHEMBL10798212 0.80 ALDH1A1 (0.46) ALDH1A1NR1H2NR1H3TSHRHDAC8
SCHEMBL2579803 0.80 NR1H2 (0.53) NR1H2NR1H3
SCHEMBL141101 0.80 ALDH1A1 (0.58) ALDH1A1NR1H2NR1H3TSHRHDAC8
SCHEMBL27193611 0.80 ALDH1A1 (0.58) ALDH1A1NR1H2NR1H3TSHRHDAC8
SCHEMBL7649599 0.80 ALDH1A1 (0.58) ALDH1A1NR1H2NR1H3TSHRHDAC8
SCHEMBL10799337 0.79 ALDH1A1 (0.44) ALDH1A1NR1H2NR1H3TSHRHDAC8
SCHEMBL3378809 0.78 NR1H2 (0.52) ALDH1A1NR1H2NR1H3TDP1
SCHEMBL10540578 0.76 NR1H2 (0.50) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2821418-B1 HYDROGENATED AROMATIC ALKENYL AND DIENE COPOLYMERS CONTAINING COMONOMERS THAT HAVE SILYL HYDRIDE UNITS AND FUNCTIONALIZED ANALOGUES THEREOF DYNASOL ELASTÓMEROS S A (ES) 2017-03-15 EP claimed
CN-104159927-B Comprise the hydrogenated alkenyl aromatic race-diene copolymers of the comonomer with silyl hydride unit and functionalized analogue thereof DYNASOL ELASTOMEROS, S.A. (ES) 2016-06-01 CN claimed
US-9238765-B2 Hydrogenated alkenyl aromatic-diene copolymers containing comonomers having silyl hydride units and their functionalized analogs DYNASOL ELASTOMEROS, S.A. (ES) 2016-01-19 US claimed
US-20150175854-A1 HYDROGENATED ALKENYL AROMATIC-DIENE COPOLYMERS CONTAINING COMONOMERS HAVING SILYL HYDRIDE UNITS AND THEIR FUNCTIONALIZED ANALOGS THE UNIVERSITY OF AKRON (US) 2015-06-25 US claimed
EP-2821418-A1 HYDROGENATED AROMATIC ALKENYL AND DIENE COPOLYMERS CONTAINING COMONOMERS THAT HAVE SILYL HYDRIDE UNITS AND FUNCTIONALIZED ANALOGUES THEREOF Dynasol Elastómeros S.A. (ES) 2015-01-07 EP claimed
US-4731424-A Process for producing polymer compound containing alkenylsilyl group SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-03-15 US claimed
JP-62263214-A None JP disclosed
JP-62215608-A None JP disclosed
JP-5220362-A None JP disclosed
US-20250043043-A1 CURABLE POLYMER, CURABLE COMPOSITION, PREPREG, MULTILAYER BODY, METAL CLAD LAMINATE AND WIRING BOARD AGC Inc. (JP) 2025-02-06 US disclosed
CN-119013318-A Curable polymer, curable composition, prepreg, laminate, metal-clad laminate, and wiring board AGC株式会社 2024-11-22 CN disclosed
WO-2023210562-A1 CURABLE POLYMER, CURABLE COMPOSITION, PREPREG, MULTILAYER BODY, METAL-CLAD LAMINATE AND WIRING BOARD AGC株式会社 2023-11-02 WO disclosed
EP-2821418-B1 HYDROGENATED AROMATIC ALKENYL AND DIENE COPOLYMERS CONTAINING COMONOMERS THAT HAVE SILYL HYDRIDE UNITS AND FUNCTIONALIZED ANALOGUES THEREOF DYNASOL ELASTÓMEROS S A (ES) 2017-03-15 EP disclosed
US-4803243-A Block-graft copolymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1989-02-07 US disclosed
US-4758640-A Vinylsilyl group-containing monodisperse polymeric compound and a method for the preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4731424-A Process for producing polymer compound containing alkenylsilyl group SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-03-15 US disclosed
US-4722975-A VINYL-CONTAINING ORGANOSILICON ETHYLENICALLY UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-02-02 US disclosed
JP-S62263214-A BLOCK COPOLYMER AND PRODUCTION THEREOF SHIN ETSU CHEM CO LTD 1987-11-16 JP disclosed
EP-0243006-A2 Block-graft copolymers and process for producing the same Shin-Etsu Chemical Co., Ltd. (JP) 1987-10-28 EP disclosed
JP-S62215608-A PRODUCTION OF ALKENYLSILYL GROUP-CONTAINING HIGH POLYMER COMPOUND SHIN ETSU CHEM CO LTD 1987-09-22 JP disclosed