Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806991 | 0.83 | TSHR (0.51) | TSHRSMN1; SMN2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL27855286 | 0.77 | HSD17B10 (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL27986032 | 0.75 | GABRA1 (0.48) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL1496075 | 0.75 | ALDH1A1 (0.72) | TSHRSMN1; SMN2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL29410575 | 0.75 | ALDH1A1 (0.72) | TSHRSMN1; SMN2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL6973845 | 0.74 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL30381190 | 0.74 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL2879819 | 0.74 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1HSD17B10 | |
| Bromide SCHEMBL29163776 | 0.73 | ALDH1A1 (0.69) | TSHRSMN1; SMN2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL10106284 | 0.73 | TSHR (0.62) | TSHRSMN1; SMN2ALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088667-B1 | HALOGENATED AROMATIC DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES | ELF ATOCHEM S.A. (FR) | 1987-04-08 | — | — | EP | disclosed |
| EP-0088667-A1 | Halogenated aromatic diamines, process for their preparation and their use in the preparation of polyurethanes | ELF ATOCHEM S.A. (FR) | 1983-09-14 | — | — | EP | disclosed |