Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803230 | 0.85 | PTGS2 (0.52) | PTGS1PTGS2 | |
| SCHEMBL10805153 | 0.83 | KCNK3 (0.63) | — | |
| SCHEMBL10803941 | 0.82 | DRD2 (0.56) | — | |
| SCHEMBL10801762 | 0.78 | — | — | |
| SCHEMBL10805187 | 0.77 | KCNK3 (0.61) | — | |
| SCHEMBL10805968 | 0.76 | KCNK3 (0.59) | — | |
| SCHEMBL10805409 | 0.72 | HTR1A (0.54) | — | |
| SCHEMBL10819114 | 0.72 | — | — | |
| SCHEMBL10799578 | 0.72 | PTGS2 (0.53) | PTGS1PTGS2 | |
| SCHEMBL10800064 | 0.71 | KCNK3 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |