Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | P2RY10 | O00398 | 3/20 | 0.37 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803365 | 1.00 | THRA (0.39) | THRATHRBCNR2CNR1P2RY10 | |
| SCHEMBL10808544 | 0.95 | LTB4R (0.38) | THRATHRBCNR2CNR1P2RY10 | |
| SCHEMBL10810929 | 0.95 | LTB4R (0.38) | THRATHRBCNR2CNR1P2RY10 | |
| SCHEMBL10811350 | 0.94 | CNR2 (0.42) | THRATHRBCNR2CNR1P2RY10 | |
| SCHEMBL10807195 | 0.94 | CNR2 (0.42) | THRATHRBCNR2CNR1P2RY10 | |
| SCHEMBL10811385 | 0.92 | ADRA1D (0.41) | THRATHRBP2RY10GPR34LTB4R | |
| SCHEMBL10809418 | 0.92 | ADRA1D (0.41) | THRATHRBP2RY10GPR34LTB4R | |
| SCHEMBL10807899 | 0.88 | CYP2D6 (0.40) | THRATHRBCNR2CNR1LTB4R | |
| SCHEMBL10808673 | 0.88 | PRKD3 (0.41) | THRATHRBP2RY10GPR34LTB4R | |
| SCHEMBL10806787 | 0.87 | LTB4R (0.39) | THRATHRBLTB4RLTB4R2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |