Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349467 | 0.80 | EIF2AK2 (0.56) | MAPK14MAPK13EIF2AK2MAPK12MAPK11 | |
| SCHEMBL9175523 | 0.66 | NPC1 (0.53) | MAPTNPC1ALDH1A1LMNARAB9A | |
| SCHEMBL14277253 | 0.64 | MAPT (0.50) | EIF2AK2MAPK12MAOBMAPTNPC1 | |
| SCHEMBL9754264 | 0.64 | KCNA3 (0.63) | MAOBMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL13147782 | 0.64 | EIF2AK2 (0.50) | MAPK14MAPK13EIF2AK2MAPK12MAPK11 | |
| SCHEMBL11714592 | 0.63 | CYP1B1 (0.46) | MAPTNPC1ALDH1A1LMNARAB9A | |
| SCHEMBL14357451 | 0.63 | MAPK14 (0.49) | MAPK14MAOBMAPTMEN1HTT | |
| SCHEMBL9173435 | 0.62 | KCNA3 (0.56) | MAOBMAPTBRD4HTT | |
| Anthraquinone SCHEMBL8469578 | 0.62 | TSHR (0.68) | MAPTNPC1ALDH1A1LMNARAB9A | |
| SCHEMBL562544 | 0.61 | TOP1 (0.67) | MAOBMAPTNPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103381-B1 | SUBSTITUTED ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONES | WARNER-LAMBERT COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |