Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805604 | 0.80 | MAPK14 (0.38) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL11120339 | 0.72 | EIF2AK2 (0.62) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL30821077 | 0.72 | EIF2AK2 (0.67) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL8171875 | 0.72 | EIF2AK2 (1.00) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL8176664 | 0.71 | EIF2AK2 (0.66) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL8172006 | 0.67 | EIF2AK2 (0.54) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| Anthraquinone SCHEMBL8469578 | 0.67 | TSHR (0.68) | ALDH1A1TSHRLMNAMEN1POLB | |
| SCHEMBL9286184 | 0.66 | EIF2AK2 (0.53) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL4846358 | 0.66 | EIF2AK2 (0.53) | EIF2AK2MAPK12MAPK13MAPK11MAPK14 | |
| SCHEMBL6524461 | 0.62 | KMT2A (0.74) | ALDH1A1MEN1POLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203697-B1 | A process for preparing substituted anthra[1,9-od]pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |
| EP-0203697-A1 | A process for preparing substituted anthra[1,9-od]pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4608439-A | Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1986-08-26 | — | — | US | disclosed |
| US-4556654-A | ANTICARCINOGENIC, FUNGICIDES, ANTISEPTICS | WARNER-LAMBERT COMPANY (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0103381-A1 | Substituted anthra(1,9-cd)pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |