Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15630516 | 0.83 | ALDH1A1 (0.36) | MAPTCASP1BLMRECQLMEN1 | |
| SCHEMBL11248712 | 0.82 | TP53 (0.40) | MAPTTP53CYP3A4CASP1BLM | |
| SCHEMBL5158945 | 0.82 | MAPT (0.51) | MAPTTP53CYP3A4CASP1BLM | |
| SCHEMBL21814428 | 0.79 | ACHE (0.40) | MAPTRECQLMEN1ALDH1A1HPGD | |
| SCHEMBL21814456 | 0.76 | ALDH1A1 (0.51) | MAPTCYP3A4SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL21814608 | 0.75 | ACHE (0.49) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL21814436 | 0.74 | ACHE (0.38) | MAPTCASP1BLMRECQLMEN1 | |
| SCHEMBL21814453 | 0.73 | ACHE (0.51) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL21814546 | 0.73 | ACHE (0.51) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL21814469 | 0.73 | ACHE (0.51) | MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101132760-A | Agent and method for colouring keratin fibres | PROCTER & GAMBLE (US) | 2008-02-27 | — | — | CN | disclosed |
| US-4704384-A | BRAIN TUMORS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1987-11-03 | — | — | US | disclosed |
| US-4233215-A | Aziridinyl quinone antitumor agents | UNITED STATES OF AMERICA (US) | 1980-11-11 | — | — | US | disclosed |
| US-4146622-A | AZIRIDINYL QUINONE ANTI-TRANSPLANTED TUMOR AGENTS | THE GOVERNMENT OF THE UNITED STATES (US) | 1979-03-27 | — | — | US | disclosed |