Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806369 | 0.82 | MAPT (0.42) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL5158945 | 0.78 | MAPT (0.51) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL11252306 | 0.68 | TDP1 (0.40) | TP53CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL15630516 | 0.66 | ALDH1A1 (0.36) | MAPTCASP1BLM | |
| SCHEMBL11681681 | 0.65 | KDM4E (0.42) | MAPTSMN1; SMN2 | |
| SCHEMBL21814428 | 0.63 | ACHE (0.40) | MAPT | |
| SCHEMBL15022768 | 0.62 | DNM1 (0.71) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL15022915 | 0.61 | DNM1 (0.50) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL14764737 | 0.61 | MAPT (0.68) | TP53CYP3A4MAPTCASP1BLM | |
| SCHEMBL21814456 | 0.60 | ALDH1A1 (0.51) | CYP3A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361516-A | N-Monosubstituted indoanilines | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-11-30 | — | — | US | disclosed |
| US-4008999-A | N,N-dialkylamino diphenylamines for dyeing keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-02-22 | — | — | US | disclosed |