Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 6/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 6/20 | 0.33 |
| ▸ | RARB | P10826 | 6/20 | 0.33 |
| ▸ | RARG | P13631 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20446707 | 1.00 | CYP1A2 (0.40) | CYP1A2HAO1RXRAGRIK1GRIK2 | |
| SCHEMBL11860416 | 0.86 | CYP1A2 (0.35) | CYP1A2HAO1RXRAGRIK1GRIK2 | |
| SCHEMBL26733276 | 0.84 | CYP1A2 (0.41) | CYP1A2HAO1RXRAGRIK1GRIK2 | |
| SCHEMBL28250392 | 0.84 | CYP1A2 (0.38) | CYP1A2HAO1RXRARARARARB | |
| SCHEMBL11316448 | 0.83 | CYP1A2 (0.40) | CYP1A2HAO1RXRAGRIK1GRIK2 | |
| SCHEMBL10946665 | 0.82 | GRIK1 (0.34) | CYP1A2HAO1RXRAGRIK1GRIK2 | |
| SCHEMBL11851829 | 0.82 | CYP1A2 (0.39) | CYP1A2HAO1RXRAGRIK1GRIK2 | |
| SCHEMBL14879927 | 0.81 | CYP1A2 (0.38) | CYP1A2HAO1RXRAGRIK1GRIK2 | |
| SCHEMBL16863841 | 0.78 | CYP1A2 (0.36) | CYP1A2HAO1RXRAGRIK1GRIK2 | |
| SCHEMBL14879860 | 0.77 | CYP1A2 (0.37) | CYP1A2HAO1RXRAGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209025-A | Process for augmenting or enhancing the flavor of tobacco using 1-(3-methylthio)butyryl)-2,6,6-trimethyl-cyclohexene and the 1,3-cyclohexadiene analog thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1980-06-24 | — | — | US | claimed |
| US-4156662-A | INTENSIFIERS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-05-29 | — | — | US | claimed |
| US-4154693-A | ORGANOLEPTIC | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-05-15 | — | — | US | claimed |
| US-4107209-A | FLAVORING, AROMA | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-08-15 | — | — | US | claimed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| EP-3416729-B1 | PRO-FRAGRANCE COMPOSITION | AQDOT LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-108601958-B | Pro-fragrance compositions | 爱客多有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| US-4156662-A | INTENSIFIERS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4156662-A | INTENSIFIERS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4154693-A | ORGANOLEPTIC | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154693-A | ORGANOLEPTIC | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154693-A | ORGANOLEPTIC | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4107209-A | FLAVORING, AROMA | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107209-A | FLAVORING, AROMA | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107209-A | FLAVORING, AROMA | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | CYP1A2 4564/4885HAO1 3269/4885RXRA 178/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | CYP1A2 4564/4885HAO1 3269/4885RXRA 178/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | CYP1A2 4564/4885HAO1 3269/4885RXRA 178/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | CYP1A2 4564/4885HAO1 3269/4885RXRA 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.