Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 7/20 | 0.31 |
| ▸ | RARB | P10826 | 7/20 | 0.31 |
| ▸ | RARG | P13631 | 6/20 | 0.30 |
| ▸ | RARA | P10276 | 5/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.30 |
| ▸ | MAPT | P10636 | 4/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.30 |
| ▸ | RXRB | P28702 | 2/20 | 0.30 |
| ▸ | RXRG | P48443 | 2/20 | 0.30 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14879927 | 0.84 | CYP1A2 (0.38) | CYP1A2HAO1GRIK1GRIK2RXRA | |
| SCHEMBL11316448 | 0.83 | CYP1A2 (0.40) | CYP1A2HAO1GRIK1GRIK2RXRA | |
| SCHEMBL26733276 | 0.81 | CYP1A2 (0.41) | CYP1A2HAO1GRIK1GRIK2RXRA | |
| SCHEMBL11851829 | 0.79 | CYP1A2 (0.39) | CYP1A2HAO1GRIK1GRIK2RXRA | |
| SCHEMBL18308880 | 0.78 | CYP1A2 (0.41) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL20446707 | 0.77 | CYP1A2 (0.40) | CYP1A2HAO1GRIK1GRIK2RXRA | |
| SCHEMBL10807261 | 0.77 | CYP1A2 (0.40) | CYP1A2HAO1GRIK1GRIK2RXRA | |
| SCHEMBL17129798 | 0.76 | CYP1A2 (0.44) | CYP1A2HAO1GRIK1RXRARARB | |
| SCHEMBL16863841 | 0.75 | CYP1A2 (0.36) | CYP1A2HAO1GRIK1GRIK2RXRA | |
| SCHEMBL14879980 | 0.75 | RXRA (0.38) | CYP1A2HAO1RXRARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768307-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| US-20170137398-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2017-05-18 | — | — | US | disclosed |
| US-9499464-B2 | Opsin-binding ligands, compositions and methods of use | BIKAM PHARMACEUTICALS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20140256782-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | BIKAM PHARMACEUTICALS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| EP-2768307-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | Bikam Pharmaceuticals, Inc. (US) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013058809-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2013-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137398-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | CRYAB, CRYAA, PDE6C | CYP1A2 4420/4885HAO1 2734/4885GRIK1 1615/4885 |
| US-20140256782-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | CRYAB, PDE6C, CRYAA | CYP1A2 4370/4885HAO1 2697/4885GRIK1 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.