Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 5/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808053 | 0.91 | TGM2 (0.46) | CASP1TGM2ALDH1A1GAAHDAC3 | |
| SCHEMBL10806798 | 0.85 | KDM4E (0.56) | TGM2HSP90AA1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22175869 | 0.83 | SLC6A4 (0.52) | HSP90AA1MAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL10362462 | 0.80 | HDAC1 (0.54) | TGM2ALDH1A1KDM4EHDAC3HDAC1 | |
| SCHEMBL10803446 | 0.79 | TGM2 (0.56) | TGM2ALDH1A1GAAKDM4EZDHHC20 | |
| SCHEMBL11017478 | 0.79 | HDAC1 (0.53) | TGM2ALDH1A1KDM4EHDAC3HDAC1 | |
| SCHEMBL10801892 | 0.79 | TGM2 (0.45) | TGM2CYP1A2HPGDCYP2C19GAA | |
| SCHEMBL9425763 | 0.79 | MAOA (0.58) | MAPTSMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL10809320 | 0.79 | GAA (0.45) | MAPTSMN1; SMN2ALDH1A1CYP1A2HPGD | |
| SCHEMBL10364129 | 0.78 | POLB (0.54) | TGM2MAPTSMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |