Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 8/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10807948 | 0.91 | CASP1 (0.46) | TGM2CASP1MTNR1AMTNR1BGAA | |
| SCHEMBL10818366 | 0.85 | TGM2 (0.50) | TGM2ITKTSHRTDP1L3MBTL1 | |
| SCHEMBL10808542 | 0.81 | ITK (0.43) | TGM2ITKTDP1L3MBTL1MAPK1 | |
| SCHEMBL10805904 | 0.81 | HPGD (0.44) | TGM2ITKTSHRTDP1L3MBTL1 | |
| SCHEMBL11017564 | 0.81 | TGM2 (0.44) | TGM2ITKTDP1GAAALDH1A1 | |
| SCHEMBL10803048 | 0.81 | KDM4E (0.46) | TGM2ITKALDH1A1LMNA | |
| SCHEMBL10803116 | 0.81 | TSHR (0.44) | TGM2TSHRL3MBTL1TP53MAPK1 | |
| SCHEMBL10807876 | 0.81 | TGM2 (0.42) | TGM2ITKALDH1A1 | |
| SCHEMBL10807794 | 0.81 | TGM2 (0.40) | TGM2ITKMTNR1AMTNR1BGAA | |
| SCHEMBL10808692 | 0.81 | TGM2 (0.40) | TGM2ITKTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |