Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 10/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803616 | 0.86 | ZDHHC2 (0.43) | LMNAGAATSHRKMT2AZDHHC20 | |
| SCHEMBL11017431 | 0.79 | ZDHHC20 (0.53) | LMNAGAATSHRKMT2AZDHHC20 | |
| SCHEMBL10811305 | 0.77 | ZDHHC20 (0.50) | GAATSHRZDHHC20ZDHHC2TGM2 | |
| SCHEMBL10808817 | 0.75 | ZDHHC20 (0.51) | GAAZDHHC20ZDHHC2TGM2ALDH1A1 | |
| SCHEMBL10364025 | 0.75 | HPGD (0.57) | KMT2AZDHHC20ZDHHC2TGM2ALDH1A1 | |
| SCHEMBL10808461 | 0.75 | TGM2 (0.44) | LMNAZDHHC20ZDHHC2TGM2ALDH1A1 | |
| SCHEMBL10808493 | 0.74 | TGM2 (0.50) | GAATSHRKMT2AZDHHC20ZDHHC2 | |
| SCHEMBL10809709 | 0.74 | ZDHHC20 (0.47) | GAATSHRKMT2AZDHHC20ZDHHC2 | |
| SCHEMBL10803272 | 0.74 | ZDHHC20 (0.47) | LMNAGAATSHRKMT2AZDHHC20 | |
| SCHEMBL92986 | 0.74 | LMNA (0.59) | LMNAGAALDHAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |