Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | VEGFA | P15692 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808559 | 1.00 | SLC6A3 (0.35) | SLC6A3SMN1; SMN2GLAPKMMIF | |
| SCHEMBL9970962 | 0.79 | MTNR1A (0.39) | MIFRAB9A | |
| SCHEMBL16153702 | 0.73 | CYP1A2 (0.40) | MIFGAATSHRHTT | |
| SCHEMBL31374595 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53LMNAHTTL3MBTL1 | |
| SCHEMBL20241203 | 0.70 | MIF (0.35) | MIFTP53GAA | |
| SCHEMBL18322173 | 0.70 | MIF (0.35) | MIFTP53GAA | |
| SCHEMBL20241204 | 0.70 | MIF (0.35) | MIFTP53GAA | |
| SCHEMBL17400432 | 0.66 | HTR2C (0.47) | — | |
| SCHEMBL23856945 | 0.65 | TSHR (0.41) | SLC6A3LMNAGAATSHRKIF11 | |
| SCHEMBL5951985 | 0.64 | CYP19A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118566-B1 | INDENO[1,2-b]PYRROLE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-03-04 | — | — | EP | disclosed |
| US-4578397-A | ANTICONVULSANTS, ANTIEPILEPTIC AGENTS, ANTIANXIETY AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1986-03-25 | — | — | US | disclosed |