Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31374595 | 0.86 | SMN1; SMN2 (0.39) | MTNR1AMTNR1BRAB9A | |
| SCHEMBL20241204 | 0.82 | MIF (0.35) | METAP1MIFEGFR | |
| SCHEMBL18322173 | 0.82 | MIF (0.35) | METAP1MIFEGFR | |
| SCHEMBL20241203 | 0.82 | MIF (0.35) | METAP1MIFEGFR | |
| SCHEMBL31374607 | 0.81 | METAP1 (0.55) | MTNR1AMTNR1BMETAP1ACHEHTR2A | |
| SCHEMBL9938389 | 0.81 | METAP1 (0.55) | MTNR1AMTNR1BMETAP1ACHEHTR2A | |
| SCHEMBL10808552 | 0.79 | SLC6A3 (0.35) | MIFRAB9A | |
| SCHEMBL10808559 | 0.79 | SLC6A3 (0.35) | MIFRAB9A | |
| SCHEMBL3842551 | 0.77 | METAP1 (0.41) | METAP1ACHERAB9AHTR2A | |
| SCHEMBL3842553 | 0.77 | METAP1 (0.41) | METAP1ACHERAB9AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021140-A1 | COMPOUND FOR DEGRADING TARGET PROTEIN | 海南先声再明医药股份有限公司 | 2025-01-30 | — | — | WO | disclosed |
| US-8946280-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| US-8946280-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| EP-2651890-B1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-14 | — | — | US | disclosed |
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-14 | — | — | US | disclosed |
| WO-2012080115-A1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | AREG, GHITM, FGF1 | MTNR1A 494/4885MTNR1B 330/4885METAP1 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.