Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805904 | 0.85 | HPGD (0.44) | TGM2ZDHHC20ZDHHC2ITKTDP1 | |
| SCHEMBL10818366 | 0.82 | TGM2 (0.50) | TGM2ITKTDP1MEN1KMT2A | |
| SCHEMBL10802404 | 0.81 | TGM2 (0.41) | TGM2ZDHHC20ZDHHC2ITKEGFR | |
| SCHEMBL10808053 | 0.81 | TGM2 (0.46) | TGM2ITKTDP1GAA | |
| SCHEMBL10808542 | 0.78 | ITK (0.43) | TGM2ZDHHC20ZDHHC2ITKTDP1 | |
| SCHEMBL10803048 | 0.78 | KDM4E (0.46) | TGM2ITKKMT2AEGFRKDR | |
| SCHEMBL11017564 | 0.78 | TGM2 (0.44) | TGM2ZDHHC20ZDHHC2ITKTDP1 | |
| SCHEMBL10803116 | 0.78 | TSHR (0.44) | TGM2MEN1KMT2AGAA | |
| SCHEMBL10807794 | 0.77 | TGM2 (0.40) | TGM2ZDHHC20ZDHHC2ITKKMT2A | |
| SCHEMBL10817754 | 0.77 | TGM2 (0.47) | TGM2ITKMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |