Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808542 | 0.91 | ITK (0.43) | HPGDITKTGM2HTTMAPT | |
| SCHEMBL10808692 | 0.85 | TGM2 (0.40) | ITKTGM2ZDHHC20ZDHHC2MEN1 | |
| SCHEMBL10818366 | 0.83 | TGM2 (0.50) | ITKTGM2NPSR1L3MBTL1MAPK1 | |
| SCHEMBL10364139 | 0.83 | HPGD (0.47) | HPGDITKTGM2HTTL3MBTL4 | |
| SCHEMBL10362307 | 0.82 | L3MBTL4 (0.61) | HPGDHTTMAPTHSP90AA1NPSR1 | |
| SCHEMBL10807841 | 0.82 | KDM4E (0.53) | HPGDITKTGM2HTTNPSR1 | |
| SCHEMBL10808053 | 0.81 | TGM2 (0.46) | ITKTGM2L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL10809331 | 0.80 | HCRTR1 (0.52) | TGM2HTTMAPTHSP90AA1NPSR1 | |
| SCHEMBL10363167 | 0.80 | TDP1 (0.58) | HPGDHTTMAPTL3MBTL1MAPK1 | |
| SCHEMBL10803116 | 0.79 | TSHR (0.44) | HPGDTGM2HTTMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652670-A | Cycloalkyl esters of mercaptoalkanoic acids | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1987-03-24 | — | — | US | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| US-4590082-A | FOR FOODS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |