Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 20/20 | 0.42 |
| ▸ | CASP7 | P55210 | 20/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 19/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 14/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.37 |
| ▸ | TSHR | P16473 | 8/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584155 | 0.84 | CASP1 (0.41) | CASP1CASP7CYP1A2CLK4ALDH1A1 | |
| SCHEMBL10813330 | 0.81 | CYP1A2 (0.36) | CASP1CASP7CYP1A2CLK4ALDH1A1 | |
| SCHEMBL9582812 | 0.75 | ALDH1A1 (0.41) | CASP1CASP7CYP1A2CLK4ALDH1A1 | |
| SCHEMBL10817902 | 0.74 | KDM4E (0.42) | ALDH1A1HSD17B10HPGD | |
| SCHEMBL10811698 | 0.71 | PDE3A (0.42) | CASP1CASP7CYP1A2CLK4ALDH1A1 | |
| SCHEMBL10818132 | 0.70 | ADORA2A (0.48) | CYP1A2ALDH1A1HSD17B10CYP3A4TSHR | |
| SCHEMBL10848496 | 0.70 | HDAC1 (0.38) | MAPK1 | |
| SCHEMBL18510348 | 0.69 | CYP1A2 (0.50) | CASP1CASP7CYP1A2CLK4ALDH1A1 | |
| SCHEMBL9583556 | 0.68 | CDK1 (0.37) | CASP1CASP7CYP1A2CLK4ALDH1A1 | |
| SCHEMBL10813342 | 0.68 | CYP1A2 (0.38) | CASP1CASP7CYP1A2CLK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105135-B1 | SUBSTITUTED 9-(1-0- OR 3-0-MONOSUBSTITUTED OR 1,3-DI-0-SUBSTITUTED 1,3 DIHYDROXY-2-PROPOXYMETHYL) PURINES AS ANTIVIRAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4609661-A | HERPES VIRUS | SYNTEX (U.S.A.) INC. (US) | 1986-09-02 | — | — | US | disclosed |
| US-4556659-A | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0105135-A1 | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-di-0-substituted 1,3 dihydroxy-2-propoxymethyl) purines as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1984-04-11 | — | — | EP | disclosed |