Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583124 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9584438 | 0.81 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10814637 | 0.78 | TMIGD3 (0.33) | ALDH1A1HSD17B10 | |
| SCHEMBL10813829 | 0.78 | ADORA2A (0.45) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10813330 | 0.76 | CYP1A2 (0.36) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1637315 | 0.76 | KDM4E (0.37) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10817918 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10814877 | 0.74 | KDM4E (0.32) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10811690 | 0.74 | CASP1 (0.42) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10818088 | 0.73 | CDC20 (0.35) | HSP90AA1HSP90AB1HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105135-B1 | SUBSTITUTED 9-(1-0- OR 3-0-MONOSUBSTITUTED OR 1,3-DI-0-SUBSTITUTED 1,3 DIHYDROXY-2-PROPOXYMETHYL) PURINES AS ANTIVIRAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4609661-A | HERPES VIRUS | SYNTEX (U.S.A.) INC. (US) | 1986-09-02 | — | — | US | disclosed |
| US-4556659-A | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0105135-A1 | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-di-0-substituted 1,3 dihydroxy-2-propoxymethyl) purines as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1984-04-11 | — | — | EP | disclosed |