Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955156 | 0.83 | LMNA (0.48) | NAPRTLMNAKMT2ATDP1CYP17A1 | |
| SCHEMBL12934601 | 0.83 | RIPK1 (0.57) | NAPRTLMNAKMT2ATDP1CYP17A1 | |
| SCHEMBL3147948 | 0.82 | KMT2A (0.51) | NAPRTLMNAKMT2ATDP1CYP17A1 | |
| SCHEMBL10615037 | 0.77 | TBXAS1 (0.56) | TBXAS1NAPRTLMNAKMT2ATDP1 | |
| SCHEMBL4056937 | 0.77 | CYP17A1 (0.43) | NAPRTLMNAKMT2ATDP1CYP17A1 | |
| SCHEMBL4664410 | 0.76 | CYP17A1 (0.46) | NAPRTLMNAKMT2ATDP1CYP17A1 | |
| SCHEMBL4665006 | 0.76 | CYP17A1 (0.46) | NAPRTLMNAKMT2ATDP1CYP17A1 | |
| SCHEMBL4665010 | 0.76 | CYP17A1 (0.46) | NAPRTLMNAKMT2ATDP1CYP17A1 | |
| SCHEMBL28994931 | 0.75 | TBXAS1 (0.61) | TBXAS1NAPRTLMNAKMT2ATDP1 | |
| SCHEMBL4245629 | 0.75 | KMT2A (0.61) | TBXAS1NAPRTLMNAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105919-B1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |