Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814457 | 0.90 | MAOA (0.40) | HPGDHSD17B10ESR1ESR2CA1 | |
| SCHEMBL10819121 | 0.81 | CYP2C19 (0.47) | HSD17B10CA1CA2CYP3A4SMN1; SMN2 | |
| SCHEMBL30523817 | 0.77 | ESR1 (0.41) | ESR1ESR2CA1CA2PGK1 | |
| SCHEMBL13753712 | 0.77 | ESR1 (0.41) | ESR1ESR2CA1CA2PGK1 | |
| SCHEMBL69546 | 0.74 | CA1 (0.42) | HPGDHSD17B10ESR1ESR2CA1 | |
| SCHEMBL19490368 | 0.74 | ALOX5 (0.36) | HPGDHSD17B10CA1CA2CYP3A4 | |
| SCHEMBL10814946 | 0.73 | ESR1 (0.34) | HPGDHSD17B10ESR1ESR2CA1 | |
| SCHEMBL28585139 | 0.73 | SHBG (0.42) | HPGDHSD17B10ESR1ESR2CA1 | |
| SCHEMBL5702537 | 0.73 | HRH3 (0.35) | HPGDHSD17B10SMN1; SMN2ALOX5 | |
| SCHEMBL2371105 | 0.71 | CA1 (0.39) | ESR1ESR2CA1CA2PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081457-B1 | PHENOLS AND THEIR USES AS STABILIZERS | CIBA-GEIGY AG (CH) | 1987-10-07 | — | — | EP | claimed |
| EP-0081457-B1 | PHENOLS AND THEIR USES AS STABILIZERS | CIBA-GEIGY AG (CH) | 1987-10-07 | — | — | EP | disclosed |