Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928677 | 0.83 | KDM4E (0.71) | ABL1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL24893527 | 0.82 | HTT (0.45) | TSHRKDM4EHSD17B10KMT2AHTT | |
| SCHEMBL4358899 | 0.79 | KDM4E (0.67) | ABL1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL4030047 | 0.79 | RAB9A (0.64) | TSHRKDM4EHTTRAB9ANPC1 | |
| SCHEMBL3708748 | 0.79 | KDM4E (0.58) | ABL1TSHRKDM4EHSD17B10MEN1 | |
| SCHEMBL417874 | 0.79 | RXFP1 (0.54) | ABL1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL6511530 | 0.78 | RXFP1 (0.48) | ABL1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL6510154 | 0.78 | KMT2A (0.63) | ABL1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL9674267 | 0.78 | ALDH1A1 (0.65) | KDM4EHSD17B10MEN1KMT2ARXFP1 | |
| SCHEMBL30556513 | 0.78 | RXFP1 (0.53) | ABL1KDM4EHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4645818-A | CONTAINING AN AMIDOARYLUREA | CIBA-GEIGY CORPORATION (US) | 1987-02-24 | — | — | US | disclosed |