Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814504 | 0.93 | FAAH (0.56) | FAAHLTB4RALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10818300 | 0.93 | FAAH (0.56) | FAAHLTB4RALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11058331 | 0.93 | FAAH (0.56) | FAAHLTB4RALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10811110 | 0.90 | FAAH (0.49) | FAAHLTB4RALDH1A1CYP1A2CASP1 | |
| SCHEMBL10813396 | 0.90 | FAAH (0.49) | FAAHLTB4RALDH1A1CYP1A2CASP1 | |
| SCHEMBL10815043 | 0.90 | LTB4R (0.51) | FAAHMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL11060626 | 0.89 | LTB4R (0.50) | FAAHMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL11059270 | 0.88 | FAAH (0.53) | FAAHMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL11060625 | 0.87 | LTB4R (0.41) | FAAHLTB4RALDH1A1CYP1A2MAPK1 | |
| SCHEMBL10816580 | 0.87 | FAAH (0.53) | FAAHLTB4RALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104342-B1 | TRIPHENYLIMIDAZOLYLOXYALCANOIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |
| US-4460598-A | Triphenylimidazolyloxyalkanoic acids and their derivatives and a process for the treatment of thromboembolic, inflammatory and/or atheriosclerotic diseases | A. NATTERMANN & CIE GMBH (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0104342-A1 | Triphenylimidazolyloxyalcanoic acids and their derivatives, process for their preparation and pharmaceutical compositions containing them | A. Nattermann & Cie. GmbH (DE) | 1984-04-04 | — | — | EP | disclosed |