Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818300 | 1.00 | FAAH (0.56) | FAAHLTB4RALDH1A1LMNANPY1R | |
| SCHEMBL10814504 | 1.00 | FAAH (0.56) | FAAHLTB4RALDH1A1LMNANPY1R | |
| SCHEMBL11059270 | 0.95 | FAAH (0.53) | FAAHLTB4RALDH1A1LMNANPY1R | |
| SCHEMBL10816580 | 0.94 | FAAH (0.53) | FAAHLTB4RALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10811110 | 0.93 | FAAH (0.49) | FAAHLTB4RALDH1A1LMNANPY1R | |
| SCHEMBL10813974 | 0.93 | FAAH (0.49) | FAAHLTB4RALDH1A1LMNANPY1R | |
| SCHEMBL10813396 | 0.93 | FAAH (0.49) | FAAHLTB4RALDH1A1CYP1A2 | |
| SCHEMBL10815671 | 0.93 | FAAH (0.52) | FAAHLTB4RALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10813329 | 0.93 | FAAH (0.52) | FAAHLTB4R | |
| SCHEMBL10810536 | 0.89 | FAAH (0.61) | FAAHALDH1A1LMNANPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460598-A | Triphenylimidazolyloxyalkanoic acids and their derivatives and a process for the treatment of thromboembolic, inflammatory and/or atheriosclerotic diseases | A. NATTERMANN & CIE GMBH (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0104342-A1 | Triphenylimidazolyloxyalcanoic acids and their derivatives, process for their preparation and pharmaceutical compositions containing them | A. Nattermann & Cie. GmbH (DE) | 1984-04-04 | — | — | EP | disclosed |