Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057526 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HTTTSHRLMNAMASP2 | |
| SCHEMBL7089269 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HTTTSHRMASP2ABCC1 | |
| SCHEMBL30761772 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HTTTSHRMASP2ABCC1 | |
| SCHEMBL27942887 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HTTTSHRLMNAMASP2 | |
| SCHEMBL10808592 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HTTTSHRABCC1 | |
| SCHEMBL10811587 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HTTHDAC3HDAC1HDAC2 | |
| SCHEMBL24505979 | 0.77 | MAPT (0.38) | ALDH1A1TSHRKDM4E | |
| SCHEMBL10704281 | 0.76 | ITGB3 (0.43) | TSHRLMNA | |
| SCHEMBL10808150 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTTTSHRMASP2ABCC1 | |
| SCHEMBL30782571 | 0.73 | GAA (0.53) | ALDH1A1HTTTSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4645818-A | CONTAINING AN AMIDOARYLUREA | CIBA-GEIGY CORPORATION (US) | 1987-02-24 | — | — | US | claimed |
| US-4677136-A | MOLDING MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-30 | — | — | US | disclosed |
| US-4645818-A | CONTAINING AN AMIDOARYLUREA | CIBA-GEIGY CORPORATION (US) | 1987-02-24 | — | — | US | disclosed |
| US-4469856-A | Non-crystalline polyamine/carbonic acid salt compositions, a process for their preparation and their use for the production of polyurethane ureas, especially foamed coatings | BAYER AKTIENGESELLSCHAFT (DE) | 1984-09-04 | — | — | US | disclosed |