Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30761772 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TSHRSMN1; SMN2HTTMASP2 | |
| SCHEMBL7089269 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TSHRSMN1; SMN2HTTMASP2 | |
| SCHEMBL27942887 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TSHRHTTMASP2LMNA | |
| SCHEMBL3648636 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KCNQ2TSHRTP53GAA | |
| SCHEMBL8779736 | 0.82 | KCNQ2 (0.50) | ALDH1A1KCNQ2TSHRTP53GAA | |
| SCHEMBL2942491 | 0.82 | KCNQ2 (0.50) | ALDH1A1KCNQ2TSHRTP53GAA | |
| SCHEMBL10814005 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TSHRHTTMASP2LMNA | |
| SCHEMBL11775098 | 0.81 | KCNQ2 (0.52) | ALDH1A1KCNQ2TSHRTP53GAA | |
| SCHEMBL20324021 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KCNQ2TSHRTP53GAA | |
| SCHEMBL11741095 | 0.79 | GPR35 (0.52) | ALDH1A1KCNQ2TSHRTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309146-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2018-04-18 | — | — | EP | disclosed |