Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 8/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15128047 | 0.86 | PYCR1 (0.67) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL11181366 | 0.80 | PYCR1 (0.57) | PYCR1MAOBALDH1A1TAAR1TSHR | |
| SCHEMBL1241075 | 0.80 | KDM4E (0.69) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL10663042 | 0.78 | PYCR1 (0.58) | PYCR1KDM4EALDH1A1LSSCXCR3 | |
| SCHEMBL3339451 | 0.78 | PYCR1 (0.58) | PYCR1KDM4EALDH1A1TAAR1CXCR3 | |
| SCHEMBL29336506 | 0.78 | PYCR1 (1.00) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL294657 | 0.77 | ALDH1A1 (0.58) | PYCR1MAOBKDM4EALDH1A1TSHR | |
| SCHEMBL1241978 | 0.77 | KDM4E (0.70) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL3161523 | 0.77 | PYCR1 (0.59) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL399795 | 0.77 | HRH3 (0.64) | PYCR1MAOBKDM4EALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4404378-A | HYPOTENSIVE AGENTS; VASODILATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1983-09-13 | — | — | US | claimed |
| EP-0063747-A1 | 2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-11-03 | — | — | EP | claimed |
| EP-0063747-B1 | 2-SUBSTITUTED OR UNSUBSTITUTED AMINOCARBONYLOXYALKYL-1,4-DIHYDROPYRIDINES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-12-09 | — | — | EP | disclosed |
| US-4404378-A | HYPOTENSIVE AGENTS; VASODILATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0063747-A1 | 2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-11-03 | — | — | EP | disclosed |