Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.56 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.56 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31432826 | 0.98 | DRD2 (0.57) | DRD2DRD4PARP10PARP11PNMT | |
| Methylamine SCHEMBL27630838 | 0.94 | DRD2 (0.53) | DRD2DRD4PARP10PARP11PNMT | |
| Acetaldehyde SCHEMBL27858363 | 0.89 | PARP10 (0.51) | DRD2DRD4PARP10PARP11PNMT | |
| SCHEMBL1556861 | 0.88 | MAPT (0.54) | DRD2DRD4PARP10PARP11PNMT | |
| SCHEMBL1264264 | 0.86 | KDM4E (0.49) | DRD2DRD4PARP10PARP11PNMT | |
| Hydrochloric Acid SCHEMBL18549588 | 0.86 | MAPT (0.53) | DRD2DRD4PARP10PARP11PNMT | |
| SCHEMBL7824837 | 0.83 | DRD2 (0.47) | DRD2DRD4PARP10PARP11PNMT | |
| SCHEMBL1612916 | 0.83 | PNMT (0.57) | DRD2DRD4PARP10PARP11PNMT | |
| SCHEMBL29414378 | 0.83 | PNMT (0.57) | DRD2DRD4PARP10PARP11PNMT | |
| SCHEMBL4899191 | 0.81 | PARP10 (0.56) | DRD2DRD4PARP10PARP11PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109670-A1 | METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE | Shanghai OuChem Bio-Technology Co., LTD (CN) | 2026-04-23 | — | — | US | claimed |
| CN-116427189-B | Fiber dyeing method and DASAs-based photochromic intelligent fabric | 电子科技大学 | 2024-07-12 | — | — | CN | claimed |
| CN-117229275-B | Novel 2-acetamido thiazole compound and preparation method and application thereof | 北京中医药大学 | 2024-06-18 | — | — | CN | claimed |
| CN-115626889-B | Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound | 南京工业大学 | 2024-04-30 | — | — | CN | claimed |
| CN-116427189-A | Fiber dyeing method and photochromic intelligent fabric based on DAAs | 电子科技大学 | 2023-07-14 | — | — | CN | claimed |
| CN-115838349-B | Preparation method of 3- (7-cyano-5- (2-oxo propyl) indoline-1-yl) propyl benzoate | 南京桦冠生物技术有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-116082213-A | Preparation method of 5-cyanoindole | 苏州永健生物医药有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-115838349-A | Preparation method of 3- (7-cyano-5- (2-oxopropyl) indolin-1-yl) propyl benzoate | 南京桦冠生物技术有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115353478-A | Preparation method of indole compound | 南京工业大学 | 2022-11-18 | — | — | CN | claimed |
| CN-109574902-B | Preparation method of silodosin intermediate | 安徽省庆云医药股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-113149886-B | Synthesis method of silodosin | 杭州乐敦科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-111072546-B | Synthesis method of 5-ethynylindoline-2, 3-diketone | 阿里生物新材料（常州）有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-113149886-A | Synthesis method of silodosin | 杭州乐敦科技有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-111454192-A | Efficient synthesis process of medical intermediate 5-bromoindole | 上海隆盛化工有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-107098845-A | A kind of preparation technology of the nitroindoline of 5 cyano group 6 | 贵州大学 | 2017-08-29 | — | — | CN | claimed |
| JP-6128226-A | — | — | None | — | — | JP | disclosed |
| US-20260146035-A1 | FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS | DONG-A ST CO., LTD. (KR) | 2026-05-28 | — | — | US | disclosed |
| US-4663453-A | Benzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepines having dopamine receptor activity | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0129692-A2 | Dibenzodiazepin derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-01-02 | — | — | EP | disclosed |
| US-4377699-A | REACTING INDOLINE WITH AN ORGANIC CARBOXYLIC ACID ACYLATING AGENT, CHLORINATION, SAPONIFICATION, FOLLOWED BY OXIDATION WITH AN AROMATIC NITRO COMPOUND | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1983-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260109670-A1 | METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE | NAT1, AADAC, NAA15 | DRD2 2300/4885DRD4 1939/4885PARP10 1168/4885 |
| US-20260146035-A1 | FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS | AXL, ERBB2, ERBB3 | DRD2 1870/4885DRD4 2042/4885PARP10 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.