Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811110 | 0.96 | FAAH (0.49) | FAAHLTB4RPPARGHDAC3HDAC4 | |
| SCHEMBL10814504 | 0.93 | FAAH (0.56) | FAAHLTB4RHDAC3HDAC4HDAC1 | |
| SCHEMBL10818300 | 0.93 | FAAH (0.56) | FAAHLTB4RHDAC3HDAC4HDAC1 | |
| SCHEMBL11058331 | 0.93 | FAAH (0.56) | FAAHLTB4RHDAC3HDAC4HDAC1 | |
| SCHEMBL10812727 | 0.92 | LTB4R (0.53) | FAAHLTB4RPPARGFABP3FABP4 | |
| SCHEMBL10816580 | 0.91 | FAAH (0.53) | FAAHLTB4RHDAC3HDAC4HDAC1 | |
| SCHEMBL11056903 | 0.91 | LTB4R (0.52) | FAAHLTB4RPPARGFABP3FABP4 | |
| SCHEMBL10813329 | 0.90 | FAAH (0.52) | FAAHLTB4RFABP3FABP4MAPT | |
| SCHEMBL11056892 | 0.89 | LTB4R (0.43) | FAAHLTB4RPPARGFABP3FABP4 | |
| SCHEMBL11059270 | 0.88 | FAAH (0.53) | FAAHLTB4RFABP3FABP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104342-B1 | TRIPHENYLIMIDAZOLYLOXYALCANOIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |
| US-4460598-A | Triphenylimidazolyloxyalkanoic acids and their derivatives and a process for the treatment of thromboembolic, inflammatory and/or atheriosclerotic diseases | A. NATTERMANN & CIE GMBH (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0104342-A1 | Triphenylimidazolyloxyalcanoic acids and their derivatives, process for their preparation and pharmaceutical compositions containing them | A. Nattermann & Cie. GmbH (DE) | 1984-04-04 | — | — | EP | disclosed |