Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682219 | 0.73 | CYP3A4 (0.44) | MAPTL3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL166418 | 0.71 | — | — | |
| SCHEMBL5638626 | 0.69 | DPP4 (0.36) | MAPTCYP3A4ALDH1A1 | |
| SCHEMBL8892656 | 0.68 | — | — | |
| SCHEMBL1243795 | 0.67 | HDAC3 (0.37) | MAPTL3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL9000514 | 0.67 | CYP3A4 (0.37) | MAPTL3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL1754879 | 0.66 | CYP3A4 (0.35) | MAPTCYP3A4ALDH1A1 | |
| SCHEMBL979256 | 0.66 | CYP3A4 (0.35) | MAPTCYP3A4ALDH1A1 | |
| SCHEMBL29170967 | 0.66 | ALDH1A1 (0.40) | MAPTCYP3A4ALDH1A1 | |
| SCHEMBL7615262 | 0.66 | CYP3A4 (0.35) | MAPTL3MBTL1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687850-A | DISTILLATION WITH BASE | THE B.F. GOODRICH COMPANY (US) | 1987-08-18 | — | — | US | claimed |
| EP-0184154-A1 | Purification of 1-(2-Amino-2-alkylpropyl)-3,3,5,5,-tetraalkylpiperazinones | The B.F. GOODRICH Company (US) | 1986-06-11 | — | — | EP | claimed |
| US-4687850-A | DISTILLATION WITH BASE | THE B.F. GOODRICH COMPANY (US) | 1987-08-18 | — | — | US | disclosed |
| EP-0184154-A1 | Purification of 1-(2-Amino-2-alkylpropyl)-3,3,5,5,-tetraalkylpiperazinones | The B.F. GOODRICH Company (US) | 1986-06-11 | — | — | EP | disclosed |