Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166418 | 0.81 | — | — | |
| SCHEMBL28634889 | 0.79 | DPP4 (0.33) | POLBALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15348022 | 0.79 | ALDH1A1 (0.31) | POLBALDH1A1 | |
| SCHEMBL10968482 | 0.79 | POLB (0.35) | CYP3A4POLBALDH1A1MAPTKMT2A | |
| SCHEMBL11388691 | 0.79 | KDM4E (0.38) | CYP3A4POLBALDH1A1MAPTKMT2A | |
| SCHEMBL8958844 | 0.78 | CYP3A4 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10964834 | 0.76 | POLB (0.33) | CYP3A4POLBALDH1A1MAPTKMT2A | |
| SCHEMBL1277501 | 0.75 | MEN1 (0.37) | CYP3A4POLBALDH1A1MAPTKMT2A | |
| SCHEMBL27967528 | 0.75 | POLB (0.35) | CYP3A4POLBALDH1A1MAPTKMT2A | |
| SCHEMBL29170967 | 0.74 | ALDH1A1 (0.40) | CYP3A4POLBALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170146549-A1 | ISOBARIC MASS LABELS | ELECTROPHORETICS LIMITED (GB) | 2017-05-25 | — | — | US | disclosed |
| EP-3155436-A1 | ISOBARIC MASS LABELS | Electrophoretics Limited (GB) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015189413-A1 | ISOBARIC MASS LABELS | ELECTROPHORETICS LIMITED (GB) | 2015-12-17 | — | — | WO | disclosed |
| US-8679773-B2 | Kits pertaining to analyte determination | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2014-03-25 | — | — | US | disclosed |
| EP-2251334-B1 | Labeling reagents and labeled analytes | DH TECHNOLOGIES DEV PTE LTD (SG) | 2013-08-14 | — | — | EP | disclosed |
| US-8273706-B2 | Isobarically labeled analytes and fragment ions derived therefrom | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2012-09-25 | — | — | US | disclosed |
| US-20110217720-A1 | Compositions and Kits Pertaining to Analyte Determination | PAPPIN DARRYL J C | 2011-09-08 | — | — | US | disclosed |
| EP-1588145-B1 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | LIFE TECHNOLOGIES CORP (US) | 2011-07-06 | — | — | EP | disclosed |
| US-7947513-B2 | Sets and compositions pertaining to analyte determination | DH Technologies Ptd. Ltd. (SG) | 2011-05-24 | — | — | US | disclosed |
| US-7910059-B2 | For the determination of an analyte or analytes such as proteins, peptides, nucleic acids, carbohydrates, lipids, steroids and small molecules by mass analysis | DH TECHNOLOGIES PTE. LTD. (SG) | 2011-03-22 | — | — | US | disclosed |
| EP-1701945-A1 | LABELING REAGENTS, LABELED ANALYTES, INCLUDING MIXTURES THEREOF, AND FRAGMENT IONS DERIVED THEREFROM AND METHODS FOR THE ANALYSIS THEREOF | Applera Corporation (US) | 2006-09-20 | — | — | EP | disclosed |
| US-20060105416-A1 | Methods, compositions and kits pertaining to analyte determination | APPLERA CORPORATION (US) | 2006-05-18 | — | — | US | disclosed |
| EP-1588145-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | Applera Corporation (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2005068446-A1 | LABELING REAGENTS, LABELED ANALYTES, INCLUDING MIXTURES THEREOF, AND FRAGMENT IONS DERIVED THEREFROM AND METHODS FOR THE ANALYSIS THEREOF | APPLERA CORPORATION (US) | 2005-07-28 | — | — | WO | disclosed |
| US-20050148087-A1 | Isobarically labeled analytes and fragment ions derived therefrom | APPLERA CORPORATION | 2005-07-07 | — | — | US | disclosed |
| US-20040220412-A1 | Compositions and kits pertaining to analyte determination | APPLE CORPORATION | 2004-11-04 | — | — | US | disclosed |
| US-20040219686-A1 | Methods and mixtures pertaining to analyte determination | APPLIED BIOSYSTEMS, LLC | 2004-11-04 | — | — | US | disclosed |
| US-20040219685-A1 | Methods and mixtures pertaining to analyte determination using electrophilic labeling reagents | APPLERA CORPORATION | 2004-11-04 | — | — | US | disclosed |
| WO-2004070352-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | APPLERA CORPORATION (US) | 2004-08-19 | — | — | WO | disclosed |
| EP-0249176-A2 | Process for the preparation of 2,3-dioxo-4-oxycarbonyl piperazine derivatives | BASF Aktiengesellschaft (DE) | 1987-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105416-A1 | Methods, compositions and kits pertaining to analyte determination | SRMS, SHBG, KLK3 | HDAC3 3627/4885HDAC4 4701/4885HDAC1 4627/4885 |
| US-20050148087-A1 | Isobarically labeled analytes and fragment ions derived therefrom | KLK3, SRMS, PTMS | HDAC3 2780/4885HDAC4 4180/4885HDAC1 4395/4885 |
| US-20170146549-A1 | ISOBARIC MASS LABELS | SRMS, PTMS, QPCTL | HDAC3 1593/4885HDAC4 2896/4885HDAC1 1252/4885 |
| US-20040220412-A1 | Compositions and kits pertaining to analyte determination | KLK3, SRMS, SHBG | HDAC3 4055/4885HDAC4 4758/4885HDAC1 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.